What should we do? (我们该怎么办?)

I don't know. It's really a difficult problem. (我不知道。这真是个难题。)

It's big problem.

我不知道说什么才好。

I don't know what to say.

I'm at a loss as to what to say. (我不知道说什么才好。) at a loss “困惑不解，茫然不知所措”。

这下可难住我了。

You got me.

I have a full house. (〈打牌中的〉我是同花顺。)

You got me. (这下可难住我了。)

I don't know.

I guess you're right. (我想你是对的。)

You win. (你赢了。)

That beats me.

他特招人讨厌。

He's a nuisance. *nuisance“难对付的人，麻烦的人”。

自作自受。

You asked for it. “自己给自己找麻烦”。

哎哟!

Oops! 表示困惑、遗憾的心情，或吃惊和轻度欢喜。

You're stepping on my foot. (你踩着我脚呢。)

Oops! I'm sorry. (哎哟!对不起。)

I made a mistake. (我犯了一个错。)

My mistake. (是我的错。)

噢!不!

Oh, no!

Oh, no! I missed the flight. (噢!不!赶不上飞机了。)

You did? (真的?)

Ah, man! man表示兴奋的和吃惊的口语说法。

Oh, my goodness!

Oh, my gosh!

Good heavens!

这正是难点。

That's the hard part.